Clinical Studies

A majority of the clinical studies on Scalp Cooling to date have been done in Europe.  The use of scalp cooling is far more prevalent there with insurance being able to cover the costs in many countries.  As scalp cooling begins to grow in popularity in the US we expect additional studies to be released.  At present, there have been several clinical studies done in the United States, notably at Wake Forest Baptist Medical Center and at the University of California, San Francisco.  As results of these promising studies are released, we will add them to the site immediately.

1. Presentation, Impact and Prevention of Chemotherapy-induced Hair Loss

Wim PM Breed, Corina JG van den Hurk, Mijke Peerbooms

This study, from Expert Review of Dermatology, February 2011, presents an overview of 58 scalp cooling publications and three personal communications.

2. Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients- Results of the Dutch Scalp Cooling Registry

Wim PM Breed, Corina JG van den Hurk, Mijke Peerbooms, Lonneke van de Poll-Franse, Johan W. Nortier, Jan Willem W. Coebergh

This study, from Acta Oncologica, April 2012, collected data on scalp-cooled patients in 27 Dutch hospitals from 2006-2009.

3. The effectiveness of a scalp cooling cap in preventing chemotherapy

Päivi Kaarina Auvinen, Ulla Annikki Mähönen, Kirsi Marika Soininen, Päivi Kaarina Paananen, Päivi Helena Ranta-Koponen, Irma Esteri Saavalainen and Risto Tapio Johansson

This study from the Department of Oncology at the Kuipio University Hospital in Finland analyzed the effectiveness of scalp cooling caps in preventing alopecia among 64 patients.

4. Efficacy and safety of cooling helmets for the prevention of chemotherapy-induced alopecia: a prospective study of 911 patients

Spaëth D., Luporsi E., Coudert B., Rios M., Weber B., Uwer L., Evon P., Braun D., Rück S.

This group study from several French Physicians and Hospitals looks at the safety issues and occurrences of scalp metastases in 911 patients that had received scalp cooling therapy.

5. Allow scalp cooling during adjuvant chemotherapy in patients with breast cancer; scalp metastases rarely occur

van de Sande MA, van den Hurk CJ, Breed WP, Nortier JW.

6. Scalp-cooling by DIGNICAP system for the prevention of chemotherapy-induced hair loss in breast cancer patients.

M. Kato, Kato Breast Surgery Clinic, Kusatsu, Japan

7. Chemotherapy-Induced Alopecia

Sudjit Luanpitpong and Yon Rojanasakul, West Virginia University, Department of Pharmaceutical Sciences, Morgantown, West Virginia